- January 15: The Lovely Bones (book by Alice Sebold)
- February 5: Dear John (book by Nicholas Sparks)
- February 12: Percy Jackson and the Lightning Thief (book by Rick Riordan)
- March 5: Alice in Wonderland (book by Lewis Carroll)
- April 2: Diary of a Wimpy Kid (book by Jeff Kinney)
- April 2: The Last Song (book by Nicholas Sparks)
- June 30: The Twilight Saga: Eclipse (book by Stephenie Meyer)
- July 30: Beastly (book by Alex Flinn)
- September 17: Flipped (book by Wendelin Van Draanen)
- November 19: Harry Potter and the Deathly Hallows: Part 1 (book by J. K. Rowling)
- December 10: The Chronicles of Narnia: The Voyage of the Dawn Treader (book by C. S. Lewis)
- December 22: Gulliver's Travels (book by Jonathan Swift)
(There will be several hightly-anticipated comic book movies out this year as well. I didn't include them because they will all be R-rated as far as I could tell.)